The Kir2.1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to KCNJ2, and potassium inwardly rectifying channel subfamily J member 2. This antibody recognizes Mouse, and Rat antigen. The Kir2.1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated has been validated for the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium